Sarah Polley and Adrien Brody star in Splice (2009).
Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms’ DNA. They decide to secretly continue their work, but this time splicing in human DNA.
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Two genetic research scientists create unique life-forms by splicing together the DNA of various animals. Their goal: the “engineered animals” will produce enzymes and proteins to be used in the manufacture of pharmaceuticals.
When lead scientists Elsa Cast (Sarah Polley) and Clive Nicoli (Adrien Brody) learn that the next phase of their project will be less interesting than pushing the frontiers of genetic engineering they decide to go beyond legal, moral, and scientific boundaries by introducing human DNA into their experiments.